ABSTRACT
In two studies, serum Lp(a) was higher in FH heterozygotes with manifest CHD,91,92,119 whereas in another no difference was observed.93 This may have been because of inclusion in the former study of patients in whom the diagnosis of FH was incorrectly assigned, or because of a higher prevalence of subclinical CHD in the study showing no association between Lp(a) and symptomatic CHD; Lp(a) levels were higher in FH regardless of the presence of clinical CHD.93
