ABSTRACT

Necrotizing enterocolitis (NEC) is the most common medical

and surgical emergency affecting the gastrointestinal tract of

infants in the neonatal intensive care unit. NEC affects 15% of all preterm infants.1,2 Up to 50% of neonates who develop

NEC eventually require surgical intervention,3,4 with the

mortality rate for these patients varying from 20 to 50%,5,6

and approaching 100% for infants with pan-intestinal NEC.6

The majority of infants who develop NEC have extremely low

birth weight. As advances in neonatal medicine have resulted

in increased survival of these infants, the incidence of NEC

continues to rise.