ABSTRACT

This chapter presents a case study of a 38-year-old woman. A 38-year-old woman presented with a lump in her breast and was diagnosed with peripheral T-cell non-Hodgkin’s lymphoma stage 3A. She underwent six cycles of CHOP-21 chemotherapy; however, a PET scan revealed residual disease in her mediastinal lymph nodes. The patient underwent six cycles of CHOP-21 chemotherapy; however, a positron emission tomography scan revealed residual disease in her mediastinal lymph nodes. There are multiple erythematous macules and papules scattered diffusely over her trunk and limbs, with relative sparing of her face. The patient has developed a drug rash called toxic erythema; this was confirmed histologically from the skin biopsy. The rash is symmetrical and consists of a myriad of very small erythematous papules and macules. Sudden-onset widespread rashes are usually ‘reactive’ with the two most common underlying causes being ‘drugs or bugs’.