ABSTRACT

This chapter presents a case study of a 40-year-old woman. A 40-year-old woman is referred to the dermatology clinic with a history of erythematous skin lesions appearing on her face, neck and chest over the past six weeks. The patient complains of a burning and slight itching with the onset of new lesions that then settle over a few weeks leaving marked pigmentation on her skin. Intermittently she has developed new lesions in addition to old lesions flaring. There are multiple annular hyperpigmented macular lesions on the skin over her face, neck and upper chest. The patient was diagnosed with a fixed drug eruption (FDE), which is an interesting phenomenon where exposure to a particular medication leads to annular erythematous skin lesion(s) which heal with pigmentation. The morphology of the skin lesions in FDE is somewhat variable, however. Classically they are circular or oval, macular or bullous and heal with pigmentation.