ABSTRACT
This chapter presents a case study of a 41-year-old woman. A 41-year-old woman presents to the on-call medical team with a fever and mild malaise. She complains of a sore rash with pustules appearing on her trunk and limbs. The patient has a temperature and looks unwell. She has a widespread erythema over her trunk and limbs that is studded with multiple, small monomorphic pustules. This patient presented with a very dramatic tender skin eruption called acute generalized exanthematous pustulosis (AGEP). This is a pustular drug eruption, most likely caused in this case by penicillin. AGEP is characterized by multiple pin-point pustules which are very monomorphic in nature and appear in sheets on an erythematous background. Pateints with AGEP frequently have a fever and mild to moderate malaise. The drug implicated in AGEP should be stopped immediately if at all possible.
