ABSTRACT

This chapter presents the case study of a 63-year-old man. A 63-year-old man presents to the dermatology out-patient clinic with a slowly growing nodule on his back. There a 3 cm × 3 cm red to plum coloured, firm, non-tender, solitary nodule with a smooth surface on his back. Full skin examination does not reveal any further lesions and there is no evidence of peripheral lymphadenopathy. The differential diagnoses of a firm, indurated erythematous purple papule/nodule that remains fixed for a period of time on the trunk include sarcoid, cutaneous metastasis B-cell lymphoma, Kaposi’s sarcoma, and a keloid scar. This patient was diagnosed with cutaneous B-cell lymphoma, Cutaneous B-cell lymphoma (CBCL). Follicle centre cell lymphomas are clinically characterized as asymptomatic nodules, plaques or tumours. CBCL lesions are slow-growing, usually red to plum in colour and are firm with a smooth surface. For the other cutaneous subtypes, patients should be investigated thoroughly for nodal and extracutaneous disease.