ABSTRACT
This chapter presents the case study of a 47-year-old in-patient. He has noticed slowly progressive redness and scaling of his feet and left palm, which is minimally itchy. In addition he has extensive discolouration and brittleness of his toenails and fingernails of the left hand. He had first noticed the skin and nail changes 4 months previously. There is no family or personal history of skin/nail problems. He is an in-patient, having undergone an autologous stem cell transplantation for multiple myeloma associated with systemic amyloidosis. Prior to the transplant he had been receiving high-dose melphalan. The skin on the soles of his feet and left palm is erythematous with scaling and desquamation. Nail plates are dystrophic and brittle distally, Beau’s lines are evident and there is associated periungal erythema.
