ABSTRACT
Despite the availability of a safe and effective live-attenuated vaccine for more than 70 years, yellow fever virus (YFV) has remained widely distributed in many tropical regions of sub-Saharan Africa and South America, and still poses a signicant public health threat to the people residing in these endemic areas as well as to travelers visiting yellow fever high-risk areas [1-6]. The World Health Organization (WHO) estimates an annual incidence of 200,000 cases with 3000 deaths still occurring mainly in sub-Saharan Africa as the result of incomplete vaccine coverage in the last two decades (see https://www.who.int/crs/resources/publications/ surveillance/yellow_fever.pdf).
