ABSTRACT
The accumulated evidence suggests that sh oil has heterogeneous antiarrhythmic properties. Its effects vary according to the type of arrhythmia, the underlying cardiac disorder, amount and type of dietary sh consumption, and other factors. This chapter reviews the basic biochemistry of polyunsaturated fatty acids (PUFA) and electrophysiologic effects of omega-3 long-chain polyunsaturated fatty acids (LCPUFA), examines the antiarrhythmic properties of sh oil, and critically evaluates the available clinical evidence as to which patients may benet and who may not benet from sh oil supplementation.
