ABSTRACT

Underneath the umbrella of gluten-related disorders, celiac disease and non-celiac gluten sensitivity have an immune reaction to gluten in common and often present with overlapping clinical symptoms. Differentiating among gluten-related disorders allows clinicians to give patients specic nutritional and other medical recommendations; however, clinical and laboratory diagnosis is complex and evolving as presented in this chapter. Nutrition holds the potential to advance medical care for patients with gluten-related disorders in several ways: A dietary history can prompt diagnosis in a clinical setting. A gluten-free diet is a medical therapy. Nutritional interventions can restore nutrients depleted by disease-associated malabsorption. Lastly, nutritional therapies have been shown to improve gastrointestinal health.