ABSTRACT

To be certain of the results of a particular experiment, and to ensure reproducibility, it is important that the appropriate precautions are taken and that proper preparations are made. Many common organic reactions involve the use of air-or moisture-sensitive reagents. For these to be successful, it is essential to know how to perform the reaction under rigorously inert, anhydrous conditions. Because of the crucial importance of these reactions, most of this chapter will focus on techniques that are compatible with the use of air-and moisture-sensitive reagents. The same basic techniques are also used for less sensitive reactions, the only difference being that an inert atmosphere may not be required.