Polyphenolic compounds are one of the most common classes of secondary metabolites found in terrestrial plants and marine algae. There are fundamental differences in the chemical structures of polyphenols in both terrestrial and marine plants (Shibata et al. 2002). Phlorotannins, algal polyphenols consisting of phloroglucinol units linked to one another in various ways, occur broadly among the brown and red algae (Singh and Bharate 2006). Several studies have demonstrated the various biological benets associated with phlorotannins, including antioxidant, anticoagulant, antibacterial, anti-inammatory, and anticancer activities (Shibata et al. 2002; Mayer and Hamann 2005; Heo et al. 2008; Kong et al. 2009).