Recently, interest in mucins has been increasing in a steady fashion, particularly in pharmaceutical and cosmeceutical studies. A large number of secondary metabolites produced by microorganisms, plants, and marine organisms have attracted much attention as bioactive substances for complementary treatment of diseases. In addition, various secondary metabolites have been widely used as preventive agents for skin related diseases. In this context, marine-based sources such as animals, plants, bacteria, and fungi have been thoroughly studied and used as ways to nd new agents with certain bioactivities (Haefner 2003; Hill and Fenical 2010). To date, several cosmeceutical compounds have been extracted and characterized from marine sources (Kim et al. 2008). Marine mucin which is a common cosmeceutical, has been isolated from marine molluscs in different forms with various bioactivities. (Kimura, Gohda, and Sakurai 2003).