ABSTRACT
TC Motility of cancer cells 20 [162] TM Motility of mesothelial cells 10 [162] TE Motility of ECM fibers 0 [162]
AsurfaceC Target surface of cancer cells 175 [px] [162]
AsurfaceM Target surface of mesothelial cells 243 [px] [162]
AperimeterC Target perimeter of cancer cells 70 [px] [162]
AperimeterM Target perimeter of mesothelial cells 72 [px] [162]
λsurfaceC Compressibility of cancer cells 3 [px −2] [162]
λsurfaceM Compressibility of mesothelial cells 10 [px −2] [162]
λperimeterC Stiffness of cancer cells 5 [px −1] [162]
λperimeterM Stiffness of mesothelial cells 10 [px −1] [162]
JC,F Adhesion between cancer cells and extracellular fluid
15 [162]
JM,F Adhesion between mesothelial cells and extracellular fluid
5 [162]
JE,F Adhesion between matrix fibers and extracellular fluid
6 [162]
JC,E Adhesion between cancer cells and matrix fibers
1 [162]
JC,M Adhesion between cancer cells and mesothelial cells
1* [162]
JM,E Adhesion between mesothelial cells and matrix fibers
1 [162]
JM,M Adhesion between mesothelial cells 0.3* [162] JC,S Adhesion between cancer cells and
Petri dish 0.5 [162]
µchemC Chemotactic strength of cancer cells 30 [µM −1] [162]
Dm MMPs diffusion rate 0.02 [px 2
MCS−1] [408]
λm MMPs decay rate 0.01 [MCS−1]
[408]
αm MMPs secretion rate 0.25* [MCS−1]
[408]
Dc Chemoattractant diffusion rate 0.1 [px 2
MCS−1] [162]
λc Chemoattractant decay rate 0.001 [MCS−1]
[162]
αc Chemoattractant secretion rate 0.2 [MCS −1] [162]
TABLE C.4: OvCa Multicellular Spheroid Invasion. (∗) indicates parameters that vary in the different sets of simulations.
