ABSTRACT
Why Do We Need Photoprotection? 20
The Solar Spectrum 20
Acute Solar Damage 21
Introduction 21
Mechanism of Acute Photodamage 22
Histology of Acute Photodamage 22
Chronic Solar Damage 23
Introduction 23
Mechanism of Chronic Damage 23
Histology of Chronic Damage 24
Other Effects of Photoexposure 24
Photosensitive Reaction 24
Phototoxicity 26
Photoallergy 27
Photosensitivity Skin Disorders 27
Lupus Erythematosus (290-330 nm) 27
Xeroderma Pigmentosum (290-340 nm) 27
Chronic Actinic Dermatitis (290-360 nm) 27
Polymorphous Light Eruption (290-365 nm) 29
Hydroa Vacciniforme (290-400 nm) 29
Persistent Light Reaction (290-400 nm) 29
Solar Urticaria (290-515 nm) 29
Porphyrias (400-410 nm) 29
Miscellaneous Dermatoses 29
Carcinogenesis Related to Photoexposure 30
Mechanism of Carcinogenesis 30
Opportunities to Interrupt the Pathway 31
Initiation 31
Promotion 31
Progression 33
Immunopathology of Skin Cancer-An Apparent Paradox 33
Strategies to Block UV Light 34
Sun Exposure Avoidance 34
Sun Protective Clothing 34
Sunscreens 36
Sunscreening Agents 37
Organic Sunscreening Agents 37
Inorganic Sunscreening Agents 37
Proper Use of Sunscreens 38
Suggestions for the Future 38
References 39
WHY DO WE NEED PHOTOPROTECTION?