ABSTRACT
Figure 7.2 Cortex areas with significant increase in regional blood flow 2 min after histamine stimulus at the right lower arm projected onto a 3D anatomical reference derived from magnetic resonance imaging. Brodmann areas and corresponding structures (area 29) are given. n = 6, nine repeated scans subtraction analysis vs. three saline puncture controls. *Areas also described by Hsieh et al. (From Refs. 22,25,26.)
Figure 8.3 Dermal nerve fibers as stained for neurofilaments (arrows) in close proximity to blood vessels and inflammatory cells (stars). Immunoperoxidase staining. Figure 8.4 Small sensory nerve fiber (arrow) as visualized by the expression of CGRP in the papillary dermis. Positive immunofluorescence staining for CGRP depicted in red pseudocolors. Confocal laser scanning microscopy. Figure 8.5 Intraepidermal nerve fiber as immunostained for PGP 9.5 (arrows). The tortuous course can be best demonstrated by optical sectioning using confocal laser scanning microscopy (optical sections a--e). Keratinocytes (K), junctional zone of epidermis, and dermis (stars). The positive immunofluorescence staining is depicted in red pseudocolors. Figure 8.6 Expression of sensory neuropeptides within axons of different nerve fibers (a--e) suggesting a variable codistribution of autonomic and sensory fibers. Positive immunofluorescence staining for CGRP depicted in red pseudocolors. Confocal laser scanning microscopy.
