ABSTRACT

Introduction 161 Stratum Corneum Mechanical Competence 162

Introduction 162 Review of Indentation Research 163

Measurement Principles 164 Introduction 164 Hardware 165

Indentometer Actuator and Needle 165 Positioning System 166 Mounting Components 166 Force Measurement 168 Computer Control 168

Taking and Interpreting Measurements 169 Position Testing of Needle Relative to Surface 169 Indentation of Human Stratum Corneum 169

Discussion and Pitfalls 172 Further Development 174 Discussion and Conclusion 175 References 176

The stratum corneum provides an important physical barrier that protects the body from desiccation. infection, and minor traumata. The "competence" of the stratum corneum in providing physical protection against injury depends on its biomechanical properties. This protective property is often thought of as "hardness" but is better described as increased stiffness, tensile strength, and mass.