ABSTRACT

Hormone therapy is an effective treatment for prostate cancer and continues to have a key role in the management of the disease.1 It is the only initial systemic treatment available for the man with advanced disease. Despite prostate-specific antigen (PSA) testing, many men still have incurable disease at diagnosis, and failure of curative treatment is often seen as an indication for hormonal treatment.2 Disease presenting at an advanced stage where hormonal treatment is the only option continues to be common in many countries. Paradoxically, there may well now be more men who are candidates for hormonal treatment than ever before. There is also considerable interest in exploring the merits of adjuvant treatment3

(Chapter 91)[CN]—the urologic equivalent of tamoxifen in breast cancer.