ABSTRACT

After the separation of arthropods and vertebrates from the last common ancestor of bilaterians about 550 million years ago, extant arthropods continue to share multiple conserved pathway components in the biosynthesis of peptide, steroid, and terpenoid (unsaturated hydrocarbon) hormones with those in the vertebrates. In the hope of achieving different potential applications, such as drug design or manipulation of the organisms, the regulation of the production

Abstract .................................................................................................................... 15 Keywords ................................................................................................................. 16 2.1Sesquiterpenoids Methyl Farnesoate and Juvenile Hormones ....................... 16 2.2Sesquiterpenoid Hormone Catalytic Enzymes (FAMeT and JHAMT) ......... 19 2.3Let’s Rethink the Discovery of JHAMT in the First Crustacean

Genome: Can Daphnia Be a Pancrustacean “Living Fossil” for Arthropod Endocrinology and Ecotoxicology?.............................................. 21

2.4MicroRNA as New Targets for Regulation of Sesquiterpenoid Production and Action....................................................................................24

References................................................................................................................26