ABSTRACT

There are many factors that influence the ability to get the correct result with any trace element technique. Unfortunately with ICP-MS, the problem is magnified even more because of its extremely high sensitivity. So, in order to ensure that the data reported is an accurate reflection of the sample in its natural state, the analyst must not only be aware of all the potential sources of contamination, but also the many reasons why analyte loss is a problem in ICP-MS. Figure 15.1 shows the major factors than can impact the analytical result in ICP-MS.