ABSTRACT

A 24 year-old Asian man presents with a persistent cough. A sputum sample is taken and cultured on Lowenstein-Jensen medium, appearing as brown, granular colonies after several weeks. The organism implicated is:

A Coxiella burnetti B Streptococcus pneumoniae C Mycobacterium tuberculosis D Legionella pneumophilia E Mycobacterium leprae

A 24-year-old HIV-positive Asian man presents with a cough. A Mantoux test is performed. After 72 hours, the wheal diameter is measured at 5.8 mm. This indicates:

A He has never been exposed to TB B He has been exposed to TB C He has had a BCG vaccination in the past D He has latent TB which is now reactivated E It is not possible to say

An 18-year-old university student develops a lower lobe pneumonia, with a raised white cell count and CRP. A sputum culture reveals a Gram-positive optochin-sensitive diplococcus. The most likely causative agent is:

A Staphylococcus aureus B Streptococcus viridans C Mycoplasma pneumoniae D Streptococcus pneumoniae E Haemophilus influenzae

A 58-year-old Caucasian alcoholic man presents to his GP with a history of sudden onset high fever, flu-like symptoms and, thick, blood stained sputum. A chest X-ray is arranged which shows marked upper lobe cavitation. The most likely causative agent is:

A Klebsiella pneumoniae B Mycobacterium tuberculosis C Staphylococcus aureus D Moraxella catarrhalis E Pnemocystis jirovecii

A 27-year-old intravenous drug user presents with a 2-week history of fevers, weight loss and a systolic murmur. The most likely causative agent is:

A Streptococcus viridans B Candida albicans C Staphylococcus aureus D Streptococcus bovis E Kingella

A patient with shingles is treated with an anti-viral. The drug used is a guanosine analogue and acts as a substrate for viral thymidine kinase. The most likely drug she has been given is:

A Foscarnet B Lamivudine C Cidofovir D Acyclovir E Ganciclovir

According to the UK immunization schedule, which vaccine should be given to a 2-month-old baby who has already received DTaP (diptheria, tetanus, pertussis), IPV (polio) and Hib (Haemophilus influenzae type B) vaccines?