Quantitative Approaches for Studying the Role of Collagen in Breast Cancer Invasion and Progression

Another signicant and emerging risk factor associated with the development of breast cancer is mammographic density [1]. e appearance of breast tissue upon mammography reects variation in tissue composition. Dark regions indicate fat cells, while lighter areas signify denser tissue made up of epithelial cells and stroma [2,3]. e portion of tissue made up of denser regions is characterized as the percent mammographic density (PMD).