ABSTRACT
In recent years, there has been growing interest in the utilization of metal nanoparticles (NPs) in materials and biomedical sciences due to the characteristic intrinsic properties of these nano-objects that provide novel solutions to many challenges in these areas (Saha et al. 2012; Shenhar and Rotello 2003). In particular, metal NPs play a vital role in biomedical sciences in the area ranging from early detection to cure of diseases. Metal NPs are very versatile objects since their functional attributes arise from the metal core, and their surface coatings can be easily tailored toward specific applications. A range of functionalities can be included within a NP complex using surface chemistry that allows attachment of cell-specific ligands for targeted delivery, surface coatings to increase circulation times and enhance bioavailability, specific materials on the surface or in the NP core that enable storage of a therapeutic cargo until the target site is reached, and materials sensitive to local
3.1 Introduction .................................................................................................... 59 3.2 Enhancement of the Magnetic Force .............................................................. 62 3.3 Template Preparation for Patterning and Characterization ............................ 63 3.4 Synthesis and Characterization of MNPs .......................................................66 3.5 Formation of Structures on the Surfaces with MNPs .................................... 67 3.6 Conclusions ..................................................................................................... 73 Acknowledgments .................................................................................................... 74 References ................................................................................................................ 74
or remote actuation cues that allow controlled delivery of therapeutics to the target cells (Galvin et al. 2012).
