ABSTRACT
Trade names: Cystrin (Sanofi-Aventis), Ditropan (Ortho-McNeil), Lyrinel (JanssenCilag) Indications: Neurogenic bladder, urinary incontinence Class: Anticholinergic, Antimuscarinic, Muscarinic antagonist Half-life: 2-3 hours Clinically important, potentially hazardous interactions with: alcohol, anticholinergics, antihistamines, arbutamine, cannabinoids, clozapine, conivaptan, diphenoxylatephenothiazines, disopyramide, domperidone, haloperidol, ketoconazole, levodopa, MAO inhibitors, memantine, metoclopramide, nefopam, nitrates, parasympathomimetics, pramlintide, secretin, tricyclic antidepressants Pregnancy category: B Note: Contraindicated in patients with urinary retention, gastric retention and other severe decreased gastrointestinal motility conditions, uncontrolled narrowangle glaucoma and in patients who are at risk for these conditions.
