In the preceding chapters we formulated thermodynamic stability criterion for the stationary non-equilibrium regime (Equation 3.37). Destabilization can lead to self-organization (i.e., formation of new structures at the frictional interface, such as in situ formed tribofilms or patterns). Furthermore, in Chapter 3, we discussed the minimum entropy production principle. In a simplified form, this principle states that a dynamical system tends to evolve to the path of least resistance-in other words, minimum friction and wear. In Chapters 6 and 7 we studied various types of frictional instabilities and vibrations. Here we will review several mechanisms of frictional instabilities and self-organized patterns that can arise from such instabilities.