ABSTRACT

Serotonin [5-hydroxytryptamine (5-HT)] is a widespread monoaminergic neurotransmitter in the brain. Its neuronal population is among the rst to differentiate in the mammalian brain (Gaspar et al. 2003), playing an important role in neurogenesis (Lauder and Krebs 1978) and in several normal physiological functions and

11.1 Organization of Midbrain Dorsal Raphe Nucleus (DRN): Control of Serotonergic Neurotransmission ................................................................... 197

11.2 Midbrain DRN Modulates Salt Intake and Renal Sodium Excretion: Interaction with Lamina Terminalis .............................................................200 11.2.1 Does Activation of Serotonin Somatodendritic 5-HT1A

Receptors at DRN Control Sodium Appetite? ..................................203 11.2.1.1 Acute Systemic or Intra-DRN Injection of a 5-HT1A

Agonist Increases Sodium Intake, Whereas Its Repeated Administration Reduces Intake under Basal Conditions and after Sodium Depletion.............................204