ABSTRACT

MSCs were first isolated from bone marrow in 19707 and have been found to express markers such as STRO-1, CD146, and CD44,12 MSCs have the potential to differentiate into mesodermal lineages, which give rise to connective tissues, such as bone, cartilage, and adipose tissue.13-15 Dental mesenchymal stem cells (DMSCs) were first identified in dental pulp of human permanent teeth.16 DMSCs have also been isolated from dental pulp from exfoliated deciduous teeth,17the apical part of dental papilla,18 the dental follicle,19 and the periodontal ligament20,21 (Fig. 11.1).