ABSTRACT

Ultrasound has become an important method for the detection of congenital brain malformations in neonates. Although it does not possess the contrast and spatial resolution capabilities of computed tomography (CT) or magnetic resonance imaging (MRI), ultrasound has nevertheless proven highly effective for the diagnosis of major structural malformations and is the preferred screening study for neonates suspected of having a brain malformation1-4. For example, malformation should be suspected in any infant with an enlarged head, craniofacial dysmorphism, a chromosomal anomaly such as trisomy 13-15 or 18, spinal dysraphism, myelomeningocele, unexplained seizures, or abnormal neurologic findings2’3’5 6. In such cases, sonography through the anterior fontanelle is an ideal initial study of intracranial anatomy.