ABSTRACT
One can consider two approaches to the diagnosis and management of unexplained infertility. The rst approach is strictly scientic, with a quest for and exclusion of each known cause of infertility before the label unexplained infertility can be given. The second approach is a pragmatic approach based upon a management-oriented policy, whereby treatment is commenced after the common obstacles to fertility have been excluded [1]. The treatment of unexplained infertility essentially aims to boost fertility, usually by a combination of superovulation and close apposition of sperm and egg(s). Sometimes, the use of assisted conception techniques provides clues to the underlying diagnosis, for example, if there are problems with fertilisation that can only be detected during in vitro fertilisation (IVF) therapy.
