ABSTRACT

DEFINITIONS Barrett’s esophagus is clinically relevant only because of its strong association with esophageal adenocarcinoma (Fig. 1). Barrett’s esophagus requires endoscopic and pathologic criteria for diagnosis. To meet the criteria for Barrett’s esophagus, endoscopy must demonstrate salmon-colored mucosa in the tubular esophagus (Fig. 2) and biopsy specimens must show intestinal metaplasia with goblet cells (so-called specialized intestinal metaplasia) (Fig. 3).