ABSTRACT
Somatostatin is distributed throughout the nervous system, and in extraneural tissues of the stomach, pancreas, and intestine (Chs. 40, 48 & 51). The main site of ghrelin biosynthesis and secretion is the stomach, but it is also produced by the hypothalamus, and has marked GH-stimulating activity. It appears to be involved in the regulation of food intake (Ch. 50).
