ABSTRACT

This section gives a brief account of the discovery of the DNA double

helix [Watson (1968)]. It is a fascinating story by itself (a story of

amazing coincidences, questionable scientific ethics etc.), but here I

mainly refer to it since it helps us to appreciate what is so special

about DNA. So let us for now forget all that we know about DNA,

especially its structure and the fact that it is the carrier of the genetic

information. Back in the forties of the last century it was still not

clear what genes were about, but it was clear that there is genetic

information that can be passed on to the next generation. DNA was

then certainly not the primary suspect for carrying this information

since it seemed then to be just a dullmolecule that showed no special

activities and thus might have just some structural function. On the

other hand, proteins were known to represent a very rich class of

extremely diverse molecules. Therefore it seemed to be logical that

the composition of proteins, or a subset thereof, somehow encodes

for the genetic information.