NCX as a Key Player in the Neuroprotection Exerted by Ischemic Preconditioning and Postconditioning

Pre-and postconditioning represent two of the most effective strategies for neuroprotection. In the ischemic preconditioning phenomenon, the neuroprotection is achieved when a brief noninjurious episode of ischemia protects the brain from a subsequent lethal insult; in the postconditioning event, the neuroprotection is mediated by a modied reperfusion subsequent to a prolonged ischemic episode.