ABSTRACT

Optical coherence tomography (OCT) is a recently developed powerful biomedical imaging technology that is capable of real-time, in situ cross-sectional visualization of tissue microstructure. OCT is analogous to ultrasound B-mode imaging in that the backscattered light intensity versus the echo time delay (or depth) is measured to form an axial scan (A-mode). Multiple axial scans acquired by translating the incident beam relative to the sample generate a cross-sectional image (B-mode) and the accrual of cross-sectional images forms a three-dimensional volumetric data set.