ABSTRACT

Following the environmental problems encountered with persistent organochlorine insecticides such as DDT, aldrin, dieldrin, and heptachlor, there was renewed interest in less persistent insecticides that might be suitable alternatives. Prominent among these were two groups of neurotoxic compounds that were readily biodegradable, the organophosphorous insecticides (OPs) and the insecticidal carbamates. Both types of insecticide act at the level of the nerve synapse as cholinesterase inhibitors.