ABSTRACT
The immune system consists of a vast network of lymphoid and nonlymphoid cells, and messenger molecules, such as cytokines and chemokines, that act in an orchestrated manner to protect against infectious and neoplastic diseases. Immunotoxicology is a subdiscipline of toxicology, and the purpose of immunotoxicity testing is to obtain data useful for immunotoxicity safety assessment. Immunotoxicology evaluations are performed to detect immune alterations, stimulatory or suppressive, the immune mechanisms responsible for these alterations, and the resultant effect on susceptibility or duration of infectious, allergic, or autoimmune disease.1
