Ethnic differences in skin properties may explain disparities seen in dermatologic disorders and provide insight into appropriate differences in the management of these disorders. However, ethnic differences in skin have been minimally investigated by objective methods, and the data are often contradictory. The current experimental human model for skin is largely based upon physical and biochemical properties known about Caucasian skin. Thus, anatomical or physiological properties in skin of different races that may alter a disease process or treatment of that disease are not being accounted for.