ABSTRACT
The aim of this chapter is to present an up-to-date view of applications of chemo metrics to the analysis of infrared and Raman spectra of biological materials. Infrared (1-6) and Raman (5-10) spectra, in general, contain a wealth of valuable information about the physical and chemical properties of molecules. However, it is not always easy to extract such information from the spectra. This is particu larly true for complicated biological molecules and biological materials con sisting of many components. In order to select useful information from rather intricate infrared and Raman spectra, various spectroscopic analytical methods, such as second-derivative, difference spectra, deconvolution, and curve-fitting, have been employed. These are very useful, but all of them have disadvantages as well as advantages. Recently, two powerful methods for spectral analysis have been introduced to the fields of infrared and Raman spectroscopy. One is twodimensional (2D) correlation spectroscopy, proposed by Noda (11,12) and an other is chemometrics (33-17).
