ABSTRACT

Gestational trophoblastic disease (GTD) was probably irst described by Hippocrates around 400 BC. However, only in 1895, GTD was found to be associated with pregnancy. Gestational trophoblastic disease is a group of interrelated tumours originating from the placenta. Gestational trophoblastic disease consists of a spectrum of pregnancy-related disorders ranging from benign hydatidiform mole, clinically malignant conditions like the invasive mole and metastatic mole, to neoplastic conditions such as choriocarcinoma, placental-site trophoblastic tumour and epithelioid trophoblastic tumour (ETT).