ABSTRACT
The tumour microenvironment is an important aspect of cancer biology that contributes to tumour initiation, tumour progression and responses to therapy. Cells and molecules of the immune system are a fundamental component of the tumour microenvironment. Tumour cells express most of the same cell surface antigens (e.g. HLA antigen) as in normal cells. Many tumour cells express speciic antigens not found in similar normal cells. This is term as tumour-associated antigens (TAAs). See Fig. 25.1.
