ABSTRACT
Chromene[2H]-2-one (1), commonly referred to as coumarin, represents the parent compound of a group of naturally occurring lactones exhibiting a wide range of biological activities (Kulkarni et al. 2006). In view of their structural diversity and extensive plant origin, coumarins have been found to be useful as anti-inammatory (Fylaktakidou et al. 2004; Hadjipavlou-Litina et al. 2007) and anticancer agents (Irena 2005; Lacy and O’Kennedy 2004). They have also been employed as uorescent probes in the study of biochemical mechanisms (Katerinopoulos 2004; Khalilah et al. 2012).
