ABSTRACT

Empirical antiviral agents should be started. • HSV: Acyclovir IV 10 mg/kg every 8 hours for 21 days reduces mortality

from 60-80% to less than 25%. • Arboviruses: There is no specific treatment for encephalitis caused by

an arbovirus. Clinical severity varies between arboviruses; Japanese B encephalitis has 20% mortality.