ABSTRACT

Question 28 A 37-year-old man with a long history of changeable bowel habit and abdominal pain presents with a 5-month history of worsening tingling and burning pain in his hands and feet. On examination, he has no weakness or wasting of the distal limb muscles, and Romberg’s sign is negative, although he has impairment of vibration sense and proprioception in a glove-and-stocking distribution. Investigations reveal a macrocytic anaemia (mean corpuscular volume [MCV] 102).