ABSTRACT
Endogenous Digoxin-Like Immunoreactive Substances Are Associated with ◾ Renal insufciency ◾ Pregnancy ◾ Liver disease ◾ Heart disease: Congestive heart failure (CHF) ◾ CNS insults: Subarachnoid hemorrhage (SAH) ◾ Endocrinopathies: Insulin-dependent diabetes mellitus (IDDM) and acromegaly ◾ Neonates: Stress and elevated serum bilirubin levels ◾ Adults: Stress and drugs = spironolactone (via hyperkalemia) ◾ Polyclonal digoxin radioimmunoassays (RIAs): To clarify true increase [digoxin]
hepatic circulation make digoxin very amenable to decontamination, with both AC and MDAC.
