Lentiviral Vector Features are present in the vector systems derived from other lentiof naked or complexed DNA on certain cell types results developed on the basis of existing viruses such as retrovirus, herpes virus, adenovirus, and adeno-associated virus. Retroviral vectors allow a stable integration into the host of their viral reverse transcriptase (RT) and integrase (IN) [1]. Moreover, these vectors allow this long-term gene transfer without transferring any viral genes. The absence or the an essential feature of retroviral vectors. These murine leukemia virus (MLV)-based vectors transduce only actively dividing cells, and therefore important gene therapy targets or skeletal muscles cannot be transduced unless they are induced to proliferate.