ABSTRACT

Chapter 6 described the overall structure of protein. This chapter describes structures of the regions related to enzyme functions. The first half of the chapter deals with cofactors, and the rest discusses the methods to study the active site structure. 7.1 Active Site and Active Center

In the previous chapters, the term active site was used without definition. The active site means the region (area or place) of enzyme protein where substrate binds and is transformed to product. For the same meaning, the active center has been used. The “center” means “point.” However, accumulation of 3D structures of enzyme has shown that the region of enzyme related to the function is broad in space. Therefore, it seems better to use the term “active site.”