It is the responsibility of all organizations that work with biological agents and toxins to operate safely and securely. Biorisk management, as defined by CEN Workshop Agreement (CWA) 15793:2011, is “a system or process to control safety and security risks associated with the handling or storage and disposal of biological agents and toxins in laboratories and facilities.” Effectively implementing this type of management is a complex process that involves all organizational stakeholders and institutional levels. It takes time, resources, and continual oversight and effort to create and sustain a highly effective biorisk management system in any organization.