In this chapter, we discuss the influence of the intrinsic shape

of membrane-attached nanoparticles on the elastic properties of

bilayer membranes. The intrinsic shape of membrane-attached

proteins is described within two different models. In the first, the

membrane-attached proteins are considered as one-dimensional

rod-like structures. In the second model the attached proteins

are considered as small two-dimensional plates. The role of the

hydrophobic protrusion of the attached nanoparticles which is

embedded in the outer lipid layer is also discussed.