ABSTRACT
Reactions to contrast media vary depending on the type of agent used, with higher incidences of reactions occurring in ionic as opposed to non-ionic agents. While reactions to intravenous (IV) contrast can be delayed, it is the immediate, acute reaction that is more relevant to the on-call radiologist. Clinical features of a contrast medium reaction are varied, ranging from vomiting and mild urticaria to acute anaphylaxis and cardiopulmonary collapse. In such instances, radiologists, in conjunction with the referring team, should follow the departmental guidelines when making the decision to use an IV contrast medium. It is important that radiographers and radiologists involved in the administration of IV contrast have up to date life support training. An anaphylatic reaction is the most serious and life-threatening side-effect of contrast administration and requires immediate recognition and treatment. Symptoms include bronchospasm and hypotension, which may lead to cardiopulmonary arrest.
