ABSTRACT
Toxicology ...................................................................................................................................... 433 History ....................................................................................................................................... 433 Choice of the Rabbit in Toxicological Research ....................................................................... 433
Justi‹cation for Use .............................................................................................................. 433 Important Physical and Physiological Characteristics ......................................................... 435
Husbandry ................................................................................................................................. 439 Facilities ............................................................................................................................... 439 Caging ..................................................................................................................................440 Feed and Water .....................................................................................................................440 Handling and Restraint ........................................................................................................ 441
Dosing Techniques ....................................................................................................................442 Oral Administration .............................................................................................................442 Dermal Administration ........................................................................................................ 443 Ocular Administration ......................................................................................................... 443 Intravenous Administration .................................................................................................. 443 Subcutaneous Administration .............................................................................................. 443 Intramuscular Administration ..............................................................................................444 Intradermal Administration .................................................................................................444 Intraperitoneal Administration .............................................................................................444 Vaginal Administration ........................................................................................................444
